- They have been produced between January 2010 and February 2013 by Work Package 5 (WP5) of the Joint Action 1 (2010-2012) as part of the objective to “develop HTA tools and methods for improved relative effectiveness assessments”. The Model and the Guidelines will be tested in pilot assessments in WP5 Joint Action 2 (2012-2015).
The HTA Core Model® for Rapid Relative Effectiveness Assessment of Pharmaceuticals
- This Model is a specific application of The HTA Core Model® adapted for the rapid assessment of the relative effectiveness of pharmaceuticals. The Model is a tool that defines the content elements to be considered in a rapid REA and facilitates standardised reporting. The aim of the use of the Model is to share information, to avoid duplication of work, and to facilitate the adaptation of information in national REA reports and the co-production of REA reports (by multiple HTA agencies).
- The Model and the Guidelines will be tested in pilot assessments in WP5 Joint Action 2 (2012-2015). Based on the experience gained in these pilots the current version of the Model will be updated in 2015.
- Please find the Model by following this link:
The Model was open for public consultation from 1 October 2012 to 30 November 2012.
- Please find the document containing comments & responses of the HTA Core Model by following this link:
The Methodological Guidelines for Rapid Relative Effectiveness Assessment of Pharmaceuticals
- Methodological Guidelines for Rapid REA of Pharmaceuticals are guidelines on methodological challenges that are encountered by health technology assessors while performing a rapid relative effectiveness assessment of pharmaceuticals. The primary aim of the guidelines is to help the assessors of evidence interpret and process the data that are presented to them as part of a REA. The following 9 guidelines have been developed grouped within three themes:
Endpoints used for REA of pharmaceuticals
Comparators and comparisons
Levels of evidence
- The Guidelines were open for public consultation between June and October 2012.
- Please find the document of comments and responses by following this link: